FPR1 Antibody Blocking Peptide

• Applications: AC
• Concentration: 1 mg/ml

FPR1 Antibody Blocking Peptide Summary

• Specificity: This peptide is specific for NB100-56473 only.
• Protein/Peptide Type: Antibody Blocking Peptide
• Gene: FPR1

Applications/Dilutions

• Dilutions:
  • Antibody Competition
• Application Notes: This peptide is useful as a blocking peptide for NB100-56473. For further blocking peptide related protocol, click here.

Packaging, Storage & Formulations

• Storage: Store at -80C. Avoid freeze-thaw cycles.
• Buffer: Peptide dissolved in dH20. Contains no BSA.
• Preservative: No Preservative
• Concentration: 1 mg/ml

Alternate Names for FPR1 Antibody Blocking Peptide

• fMet-Leu-Phe receptor
• fMLF-R
• fMLP receptor
• FMLP
• formyl peptide receptor 1
• FPR1
• FPRfMet-Leu-Phe receptor
• N-formyl peptide receptor
• N-formylpeptide chemoattractant receptor

Background

Official Gene Symbol: FPR1 Gen Bank Accession Number: NP_002020 Gene ID: 2357 (Human) Gene Map Locus: 19q13.4 (Human) FPR1 is a member of chemoattractant/chemokine GPCRs expressed mainly on leukocytes, neutrophils and monocytes. FPR1 is a seven transmembrane pertussis toxin-sensitive GPCR and binds to formylated peptides generated by bacteria resulting in leukocyte trafficking to the site of inflammation. Ligand binding to FPR results in activation of multiple effectors including phospholipase C leading to calcium mobilization and PKC activation. Other implications of FPR signaling include polarization of actin cytoskeletion, activation of various integrins, increased cell migration, phagocytosis, degranulation and release of reactive oxygen intermediates.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: FPR1