FPR1 Products

Antibodies
FPR1 Antibody
FPR1 Antibody
NB100-56473
Species: Hu, Mu, Pm
Applications: WB, Simple Western
Host: Rabbit Polyclonal
FPR1 Antibody
FPR1 Antibody
NBP2-47452
Species: Hu
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
FPR1 Overexpression Lysate (N ...
FPR1 Overexpression Lysate (Native)
NBP2-04212
Applications: WB
Proteins
FPR1 Recombinant Protein
FPR1 Recombinant Protein
H00002357-P01
Species: Hu
Applications: WB, ELISA, PA
FPR1 Recombinant Protein Anti ...
FPR1 Recombinant Protein Antigen
NBP2-47452PEP
Species: Hu
Applications: AC
FPR1 Recombinant Protein
FPR1 Recombinant Protein
H00002357-G01
Species: Hu
RNAi
FPR1 RNAi
FPR1 RNAi
H00002357-R02
Species: Hu

Description

Official Gene Symbol: FPR1 Gen Bank Accession Number: NP_002020 Gene ID: 2357 (Human) Gene Map Locus: 19q13.4 (Human) FPR1 is a member of chemoattractant/chemokine GPCRs expressed mainly on leukocytes, neutrophils and monocytes. FPR1 is a seven transmembrane pertussis toxin-sensitive GPCR and binds to formylated peptides generated by bacteria resulting in leukocyte trafficking to the site of inflammation. Ligand binding to FPR results in activation of multiple effectors including phospholipase C leading to calcium mobilization and PKC activation. Other implications of FPR signaling include polarization of actin cytoskeletion, activation of various integrins, increased cell migration, phagocytosis, degranulation and release of reactive oxygen intermediates.

Bioinformatics

Entrez Human
Uniprot Human
Human
Product By Gene ID 2357
Alternate Names
  • fMet-Leu-Phe receptor
  • fMLP receptor
  • N-formyl peptide receptor
  • FMLP
  • FPRfMet-Leu-Phe receptor
  • N-formylpeptide chemoattractant receptor
  • formyl peptide receptor 1

Research Areas for FPR1

Find related products by research area and learn more about each of the different research areas below.

GPCR
Immunology
Protein Kinase

PTMs for FPR1

Learn more about PTMs related to FPR1.

Phosphorylation
Formylation
Cleavage
Reduction
Glycosylation
Oxidation

Bioinformatics Tool for FPR1

Discover related pathways, diseases and genes to FPR1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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