FoxP1 Antibody (4E3-G11)

Product Discontinued

FoxP1 Antibody (4E3-G11) Summary

• Immunogen: FOXP1 (AAH05055, 1 a.a. ~ 115 a.a) full length recombinant protein with GST tag.MMQESGTETKSNGSAIQNGSGGSNHLLECGGLREGRSNGETPAVDIGAADLAHAQQQQQQWHLINHQPSRSPSSWLKRLISSPWELEVLQVPLWGAVAETKMSGPVCQPNPSPF
• Specificity: FOXP1 - forkhead box P1
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: FOXP1
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Western Blot 1:500
• Application Notes: Antibody Reactive against Recombinant Protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control.

Reactivity Notes

Human. Other species not tested.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for FoxP1 Antibody (4E3-G11)

• FLJ23741
• fork head-related protein like B
• forkhead box P1
• forkhead box protein P1
• FoxP1
• glutamine-rich factor 1
• hFKH1B
• HSPC215
• MGC12942
• MGC88572
• MGC99551
• QRF1
• QRF112CC4

Background

This gene belongs to subfamily P of the forkhead box (FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription during both development and adulthood. Forkhead box P1 protein contains both DNA-binding- and protein-protein binding-domains. This gene may act as a tumor suppressor as it is lost in several tumor types and maps to a chromosomal region (3p14.1) reported to contain a tumor suppressor gene(s). Alternative splicing results in multiple transcript variants encoding different isoforms.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for FoxP1 Antibody (H00027086-M01)(2)

Publications using H00027086-M01

• Roncador G, Engel P, Maestre L et al. The European antibody network's practical guide to finding and validating suitable antibodies for research. MAbs 2015-09-29 [PMID: 26418356]
• Brown PJ, Kagaya R, Banham AH. Characterization of human FOXP1 isoform 2, using monoclonal antibody 4E3-G11, intron retention as a tissue-specific mechanism generating a novel FOXP1 isoform. Histopathology;52(5):632-7. 2008-04-01 [PMID: 18312343]

Bioinformatics

• Gene Symbol: FOXP1
• Entrez:
  • 27086(Human)
• OMIM:
  • 605515(Human)
• Uniprot:
  • AAH05055(Human)