FOXO3 Antibody (1B11)

Immunocytochemistry/Immunofluorescence: FOXO3 Antibody (1B11) [H00002309-M02] - Analysis of monoclonal antibody to FOXO3 on HeLa cell . Antibody concentration 10 ug/ml.

Immunohistochemistry-Paraffin: FOXO3 Antibody (1B11) [H00002309-M02] - Analysis of monoclonal antibody to FOXO3A on formalin-fixed paraffin-embedded human stomach. Antibody concentration 3 ug/ml.

Proximity Ligation Assay: FOXO3 Antibody (1B11) [H00002309-M02] - Analysis of protein-protein interactions between IKBKB and FOXO3. HeLa cells were stained with anti-IKBKB rabbit purified polyclonal 1:1200 and anti-FOXO3 mouse monoclonal antibody 1:50. Each red dot represents the detection of protein-protein interaction complex, and nuclei were counterstained with DAPI (blue).

ELISA: FOXO3 Antibody (1B11) [H00002309-M02] - Detection limit for recombinant GST tagged FOXO3A is approximately 0.03ng/ml as a capture antibody.

Product Discontinued

FOXO3 Antibody (1B11) Summary

• Description: Quality control test: Antibody Reactive Against Recombinant Protein.
• Immunogen: FOXO3A (AAH21224, 361 a.a. ~ 460 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. PCTVELPRLTDMAGTMNLNDGLTENLMDDLLDNITLPPSQPSPTGGLMQRSSSFPYTTKGSGLGSPTSSFNSTVFGPSSLNSLRQSPMQTIQENKPATFS
• Specificity: forkhead box O3A
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: FOXO3
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Proximity Ligation Assay
  • Sandwich ELISA
• Application Notes: Antibody reactivity against recombinant protein on ELISA. It has been used for IHC-P.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: In 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for FOXO3 Antibody (1B11)

• AF6q21 protein
• AF6q21
• DKFZp781A0677
• FKHRL1
• FKHRL1MGC31925
• FKHRL1P2
• forkhead box O3
• forkhead box protein O3
• forkhead homolog (rhabdomyosarcoma) like 1
• Forkhead in rhabdomyosarcoma-like 1
• forkhead, Drosophila, homolog of, in rhabdomyosarcoma-like 1
• FOXO2
• FoxO3
• FOXO3A
• FOXO3Aforkhead box O3A
• MGC12739

Background

This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: FOXO3
• Entrez:
  • 2309(Human)
• OMIM:
  • 602681(Human)
• Uniprot:
  • AAH21224(Human)