FoxN1 Antibody (717008) [Alexa Fluor® 350]

• Reactivity: Mu
• Applications: IHC
• Clone: 717008
• Clonality: Monoclonal
• Host: Rat
• Conjugate: Alexa Fluor 350

FoxN1 Antibody (717008) [Alexa Fluor® 350] Summary

• Immunogen: E. coli-derived recombinant mouse FoxN1
  Val2-Asp164
  Accession # Q61575
• Specificity: Detects mouse FoxN1 in direct ELISAs.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Rat
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for FoxN1 Antibody (717008) [Alexa Fluor® 350]

• FKHL20
• forkhead box N1
• forkhead box protein N1
• FoxN1
• RONU
• Rowett nude
• WHN
• WHNRONU
• winged helix nude
• winged-helix nude
• Winged-helix transcription factor nude

Background

Forkhead box N1 (FoxN1) is a 69 kDa transcriptional regulator that is primarily expressed in thymic epithelial cells and keratinocytes. FoxN1 function is required for proper T cell, hair follicle, and nail differentiation. Mutations in FoxN1 result in severe combined immunodeficiency (SCID/Nude). Mouse FoxN1 contains one DNA-binding forkhead domain (aa 271-367). Within amino acids 1 - 164, mouse FoxN1 shares 84% and 95% aa sequence identity with human and rat FoxN1, respectively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.