FoxN1 Products

Description

Forkhead box N1 (FoxN1) is a 69 kDa transcriptional regulator that is primarily expressed in thymic epithelial cells and keratinocytes. FoxN1 function is required for proper T cell, hair follicle, and nail differentiation. Mutations in FoxN1 result in severe combined immunodeficiency (SCID/Nude). Mouse FoxN1 contains one DNA-binding forkhead domain (aa 271-367). Within amino acids 1 - 164, mouse FoxN1 shares 84% and 95% aa sequence identity with human and rat FoxN1, respectively.

Bioinformatics

Uniprot	Q61575
Product By Gene ID	8456
Alternate Names	FKHL20 forkhead box N1 forkhead box protein N1 FoxN1 RONU Rowett nude WHN WHNRONU winged helix nude winged-helix nude Winged-helix transcription factor nude