Flamingo homolog 1/CELSR3 Antibody - BSA Free

Immunohistochemistry-Paraffin: Flamingo homolog 1/CELSR3 Antibody [NBP2-38975] - Staining of human Cerebellum shows moderate cytoplasmic positivity in Purkinje cells.

Immunohistochemistry-Paraffin: Flamingo homolog 1/CELSR3 Antibody [NBP2-38975] - Staining of human testis shows moderate cytoplasmic positivity in Leydig cells.

Immunohistochemistry-Paraffin: Flamingo homolog 1/CELSR3 Antibody [NBP2-38975] - Staining of human small intestine shows moderate cytoplasmic positivity in glandular cells.

Immunohistochemistry-Paraffin: Flamingo homolog 1/CELSR3 Antibody [NBP2-38975] - Staining of human skeletal muscle shows no positivity in myocytes as expected.

• Reactivity: Hu, Mu, Rt
• Applications: IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

Flamingo homolog 1/CELSR3 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit Flamingo homolog 1/CELSR3 Antibody - BSA Free (NBP2-38975) is a polyclonal antibody validated for use in IHC and WB. Anti-Flamingo homolog 1/CELSR3 Antibody: Cited in 1 publication. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: This antibody was developed against a recombinant protein corresponding to amino acids: LDSLSRSSNSREQLDQVPSRHPSREALGPLPQLLRAREDSVSGPSHGPSTEQLDILSSILASFNSSALSSVQSSSTP
• Predicted Species: Mouse (94%), Rat (94%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CELSR3
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:2500 - 1:5000
  • Immunohistochemistry-Paraffin 1:2500 - 1:5000
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended.
• Control Peptide:

  Flamingo homolog 1/CELSR3 Protein (NBP2-38975PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for Flamingo homolog 1/CELSR3 Antibody - BSA Free

• Cadherin family member 11
• cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila)
• CDHF11
• CDHF11RESDA1
• CELSR3
• EGFL1
• EGFL1cadherin EGF LAG seven-pass G-type receptor 3
• EGF-like protein 1
• EGF-like-domain, multiple 1
• epidermal growth factor-like 1
• Epidermal growth factor-like protein 1
• Flamingo homolog 1
• FMI1anchor protein
• HFMI1
• KIAA0812
• MEGF2
• MEGF2cadherin EGF LAG seven-pass G-type receptor 3, flamingo (Drosophila) homolog
• multiple EGF-like domains 2
• Multiple EGF-like domains protein 2
• Multiple epidermal growth factor-like domains protein 2
• RESDA1

Background

CELSR3 is an Orphan-U GPCR with an unknown ligand. In mouse, this gene is expressed during development at sites of active neurogenesis and in adult mice and rats in brain, spinal cord, dorsal root ganglion, and eye. ESTs have been isolated from human B-cell/lung/testis, blood, brain, colon, heart/melanocyte/uterus, lung, nerve, and placenta libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Flamingo homolog 1/CELSR3 Antibody (NBP2-38975)(1)

Publication using NBP2-38975

• Van Emmenis L, Ku S, Gayvert K et al. The identification of CELSR3 and other potential cell surface targets in neuroendocrine prostate cancer Cancer Research Communications 2023-07-13 [PMID: 37546702] (WB, Human)

Bioinformatics

• Gene Symbol: CELSR3
• Uniprot:
  • Q9NYQ7(Human)