Fibrinopeptide B Antibody (1F9)

Product Discontinued

Fibrinopeptide B Antibody (1F9) Summary

• Immunogen: Purified recombinant fragment of human FGB (aa30-300) expressed in E. coli.
• Specificity: Human FGB
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: FGB
• Purity: Unpurified

Applications/Dilutions

• Dilutions:
  • ELISA 1:10000
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 1:200-1:300
  • Western Blot 1:500-1:2000

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: Ascites
• Preservative: 0.03% Sodium Azide
• Purity: Unpurified

Alternate Names for Fibrinopeptide B Antibody (1F9)

• Beta-Fibrinogen
• FGB Peptide
• FIBB
• Fibrinogen beta chain
• Fibrinogen Type II
• fibrinogen, B beta polypeptide
• Fibrinopeptide B
• FPB
• MGC104327
• MGC120405

Background

The protein encoded by the Fibrinopeptide B gene is the beta component of fibrinogen, a blood-borne glycoprotein comprised of threepairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrinwhich is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrinregulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for severalcell types. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia,hypodysfibrinogenemia and thrombotic tendency. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: FGB
• Entrez:
  • 2244(Human)
• Uniprot:
  • P02675(Human)