FAT4 Antibody

Images

 
Western Blot: FAT4 Antibody [NBP2-78795] - Samples: Whole cell lysate (50 ug) from HeLa and KM12 cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-FAT4 antibody NBP2-78795 used for WB at ...read more
Immunoprecipitation: FAT4 Antibody [NBP2-78795] - Samples: Whole cell lysate (1.0 mg per IP reaction; 20% of IP loaded) from HeLa cells prepared using NETN lysis buffer. Antibodies: Affinity purified rabbit anti-FAT4 ...read more

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

FAT4 Antibody Summary

Immunogen
between 4931 and 4981
Predicted Species
Mouse (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
FAT4
Purity
Affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:1000
  • Immunoprecipitation 8-15 ul/mg

Packaging, Storage & Formulations

Storage
Store at 2 - 8 C / 1 year from date of receipt
Buffer
TBS containing 0.1% BSA
Preservative
0.09% Sodium Azide
Purity
Affinity purified

Alternate Names for FAT4 Antibody

  • cadherin family member 14
  • cadherin-related family member 11
  • CDHR11
  • FAT tumor suppressor homolog 4 (Drosophila)
  • FAT-J
  • fat-like cadherin protein FAT-J
  • FLJ77878
  • hFat4
  • NBLA00548
  • putative protein product of Nbla00548

Background

FAT4 (FAT tumor suppressor homolog 4, also know as Fat-J, mFat4, and CDHF14) is a member of the Cadherin superfamily. Members of the Cadherin superfamily positively regulate planar cell polarity (PCP) in drosophila wings and play an important role in cell to cell adhesion interactions. FAT4 and other Cadherin family members have been used in systems medicine; especially in the fields of oncology and neurology (PMID: 16865240). FAT4 is widely expressed in most tissues, especially fetal and infant brain. It is also expressed in brain tumors and colorectal cancer. Furthermore, human breast tumor cell lines and primary tumors show a loss of FAT4 expression. Promoter methylation of a FAT4 allele can inactivate the expression of the FAT4 gene in deleted regions of the Hippo signaling pathway, the pathway that controls organ size (PMID: 19048595).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol FAT4
Uniprot