Fast skeletal myosin light chain 1 Antibody (BGN/0992/6H8)

Product Discontinued

Fast skeletal myosin light chain 1 Antibody (BGN/0992/6H8) Summary

• Immunogen: Synthetic peptide corresponding to part of the chicken myosin light chain
• Specificity: This product recognizes chicken myosin light chain, a component of the myosin complex that functions in muscle contraction.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: MYL1
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000

Reactivity Notes

Reacts with: Bovine, Rabbit

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.09% Sodium Azide
• Purity: Protein A or G purified

Alternate Names for Fast skeletal myosin light chain 1 Antibody (BGN/0992/6H8)

• A1 catalytic
• A2 catalytic
• MLC1/MLC3
• MLC1F
• MLC1F/MLC3F
• MLC3F
• myosin light chain 1/3, skeletal muscle isoform
• Myosin light chain A1/A2
• Myosin light chain alkali 1/2
• myosin, light chain 1, alkali; skeletal, fast
• myosin, light polypeptide 1, alkali; skeletal, fast

Background

Myosin II is the so called "classical" myosin, being the first type of myosin to be discovered. Myosin II forms bipolar filaments that interact with actin filaments to produce contraction. Myosin II was first isolated from muscle but is also found in non muscle cells, and it is especially enriched in highly motile cell types such as amoebae. The myosin II molecule is composed of two heavy chains and two sets of light chains. The light chains are the Essential Light Chains (ELC) and Regulatory Light Chains (RLC). Overall activity and polymerization can be modulated by phosphorylation on the light chains and the C terminus of the heavy chains respectively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: MYL1