FARP1 Antibody

Product Discontinued

FARP1 Antibody Summary

• Immunogen: Peptide with sequence GEIEQRPTPGSRL-C corresponding to N-Terminus according to NP_005757.1, NP_001001715.2.
• Specificity: This antibody is expected to recognize isoform 1 (NP_005757.1) and isoform 2 (NP_001001715.2).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: FARP1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry 10 ug/mL
  • Immunocytochemistry/ Immunofluorescence 10 ug/mL
  • Peptide ELISA Detection limit 1:32000

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Mouse, Rat, Bovine.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris (pH 7.3), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Notes

Please note, this antibody is considered Innovators Grade. Innovators Grade antibodies are generally unvalidated and require additional characterization for most new species/applications. Novus has made these antibodies available through our Innovators Reward program. Complete an online review with image, detailing your positive or negative results. In return, you receive a discount voucher for 100% of the purchase price of the reviewed product. Please contact us at innovators@novusbio.com for more details.

Alternate Names for FARP1 Antibody

• CDEPPleckstrin homology domain-containing family C member 2
• Chondrocyte-derived ezrin-like protein
• FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
• FERM, RhoGEF and pleckstrin domain-containing protein 1
• MGC87400
• PLEKHC2PH domain-containing family C member 2

Background

This gene was originally isolated through subtractive hybridization due to its increased expression in differentiated chondrocytes versus dedifferentiated chondrocytes. The resulting protein contains a predicted ezrin-like domain, a Dbl homology domain, and a pleckstrin homology domain. It is believed to be a member of the band 4.1 superfamily whose members link the cytoskeleton to the cell membrane. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for FARP1 Antibody (NB300-905)(1)

Publication using NB300-905

• Koyano Y, Kawamoto T, Shen M et al. Molecular cloning and characterization of CDEP, a novel human protein containing the ezrin-like domain of the band 4.1 superfamily and the Dbl homology domain of Rho guanine nucleotide exchange factors. Biochem Biophys Res Commun 1997-12-18 [PMID: 9425278]

Bioinformatics

• Gene Symbol: FARP1
• Entrez:
  • 10160(Human)
• Uniprot:
  • NP_005757(Human)