FAK [p Tyr397] Antibody

Product Discontinued

FAK [p Tyr397] Antibody Summary

• Immunogen: Synthetic phosphopeptide derived from human FAK around the phosphorylation site of Serine 397.
• Modification: p Tyr397
• Marker: Focal Adhesion Marker
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PTK2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:50-1:200
  • Western Blot 1:500-1:1000
• Application Notes: Western blot (WB) analysis of p-FAK (Y397) pAb in extracts from Jurkat cellsImmunohistochemistry (IHC) analyzes of p-FAK (Y397) pAb in paraffin-embedded human brain tissue. Immunocytochemistry/Immunofluorescence was reported in scientific literature.
• Theoretical MW: 125 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
• Control:

  FAK Overexpression Lysate

Reactivity Notes

This antibody is reactive against Human, Mouse, Rat.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2)
• Preservative: 0.05% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for FAK [p Tyr397] Antibody

• EC 2.7.10
• FADK 1
• FADK1
• FADKFAK-related non-kinase polypeptide
• FAK
• FAK1FRNK
• FAKEC 2.7.10.2
• focal adhesion kinase 1
• pp125FAK
• Protein-tyrosine kinase 2
• PTK2 protein tyrosine kinase 2
• PTK2

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for FAK Antibody (NB100-92712)(2)

Publications using NB100-92712

• Cheng WY, Chiao MT, Liang YJ et al. Luteolin inhibits migration of human glioblastoma U-87 MG and T98G cells through downregulation of Cdc42 expression and PI3K/AKT activity. Mol Biol Rep 2013-05-16 [PMID: 23677714] (WB, Human)
• Kim DH, Khatau SB, Feng Y et al. Actin cap associated focal adhesions and their distinct role in cellular mechanosensing Sci Rep 2012-01-01 [PMID: 22870384] (ICC/IF)

Bioinformatics

• Gene Symbol: PTK2
• Entrez:
  • 5747(Human)
  • 25614(Rat)