FAIM3 Antibody

Product Discontinued

FAIM3 Antibody Summary

• Immunogen: A 13 amino acid peptide from near the carboxy terminus of human Toso.
• Specificity: 13 amino acid peptide from near the carboxy terminus of human Toso
• Clonality: Polyclonal
• Host: Rabbit
• Gene: FCMR
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 5 ug/ml
  • Western Blot 1 ug/ml

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for FAIM3 Antibody

• FAIM3
• Fas apoptotic inhibitory molecule 3
• Fc mu R
• Fc mu receptor
• FCMR
• immunoglobulin mu Fc receptor
• Regulator of Fas-induced apoptosis Toso
• Toso
• TOSOIgM Fc receptor

Background

FAIM3 may play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream. May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: FCMR
• Entrez:
  • 9214(Human)
• Uniprot:
  • O60667()