Species: Hu, Mu
Applications: WB, ELISA, Flow, IHC
Host: Mouse Monoclonal
Species: Hu, Mu, Rt
Applications: WB, Flow, CyTOF-ready
Host: Mouse Monoclonal
Species: Hu
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: ELISA
Species: Hu
Applications: WB
Species: Hu
Applications: WB
Species: Hu
Applications: Bioactivity
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
FAIM3 may play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream. May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation.
Bioinformatics
Entrez |
Human |
Uniprot |
Human Human Human Human Human Human |
Product By Gene ID |
9214 |
Alternate Names |
- Fas apoptotic inhibitory molecule 3
- Fc mu receptor
- FCMR
- immunoglobulin mu Fc receptor
- Regulator of Fas-induced apoptosis Toso
- TOSOIgM Fc receptor
|
Research Areas for FAIM3
Find related products by research area and learn more about each of the different research areas below.
Apoptosis