ERCC6L Antibody [Alexa Fluor® 350]

• Reactivity: Hu
• Applications: IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Alexa Fluor 350

ERCC6L Antibody [Alexa Fluor® 350] Summary

• Immunogen: Produced in rabbits immunized with E. coli-derived Human ERCC6L fragment.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: ERCC6L
• Purity: Antigen and protein A Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry-Paraffin
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Antigen and protein A Affinity-purified

Notes

Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for ERCC6L Antibody [Alexa Fluor® 350]

• ATP-dependent helicase ERCC6-like
• DNA excision repair protein ERCC-6-like
• EC 3.6.1
• EC 3.6.4.12
• excision repair cross-complementing rodent repair deficiency, complementationgroup 6-like
• excision repair protein ERCC6-like
• FLJ20105
• MGC131695
• PICHexcision repair cross-complementing rodent repair deficiency complementationgroup 6 - like
• PLK1-interacting checkpoint helicase
• SNF2/RAD54 family protein
• Tumor antigen BJ-HCC-15

Background

DNA helicase that acts as an essential component of the spindle assembly checkpoint. Contributes to the mitotic checkpoint by recruiting MAD2 to kinetochores and monitoring tension on centromeric chromatin. Acts as a tension sensor that associates with catenated DNA which is stretched under tension until it is resolved during anaphase

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ERCC6L