EphA5 Antibody (86731) [HRP]

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Product Details

Summary
Reactivity Hu, RtSpecies Glossary
Applications WB
Clone
86731
Clonality
Monoclonal
Host
Mouse
Conjugate
HRP

EphA5 Antibody (86731) [HRP] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant rat EphA5
Ser58-Gln573 (Asp170Glu)
Accession # P54757
Specificity
Detects rat EphA5 in direct ELISAs and Western blots. In direct ELISAs, 5‑15% cross reactivity with recombinant mouse (rm) EphA4 and rmEpha8 is observed and no cross-reactivity with recombinant human (rh) EphA1, rmEphA2, -A3, -A6, -A7, recombinant rat EphB1, -B2, or rmEphB3 is observed.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
EPHA5
Purity
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

0

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
No Preservative
Purity
Protein A or G purified from hybridoma culture supernatant

Alternate Names for EphA5 Antibody (86731) [HRP]

  • Bsk
  • Cek7
  • EC 2.7.10
  • EC 2.7.10.1
  • Ehk1
  • EHK-1
  • EHK1Hek7
  • EK7
  • EPH homology kinase 1
  • Eph homology kinase-1
  • EPH receptor A5
  • EphA5
  • EPH-like kinase 7
  • ephrin type-A receptor 5
  • Hek7
  • receptor protein-tyrosine kinase HEK7
  • Rek7
  • TYRO4HEK7CEK7
  • tyrosine-protein kinase receptor EHK-1

Background

The EPHA5 gene encodes a member of a subfamily of the protein-tyrosine kinase family, an ephrin type-A receptor 5 receptor that exists in three isoforms: isoform 1: 1,037 amino acids long at 114 kDA; isoform 2: 1,015 amino acids long, 112 kDA; and isoform 3: 969 amino acids long at 107 kDA. Receptors of this family function in mediating developmental events especially in the nervous system. EPHA5 participates in the JNK pathway, P2Y receptor signaling, paxillin interactions, intracellular calcium signaling, and EphrinA-ephR signaling. It interacts with genes EFNA2, EFNA1, EFFNA3, EFNA5, and STAT3. EPHA4 is linked to pancreatitis, glioblastoma, cerebritis, ovarian cancer, adenocarcinoma, breast cancer and drug psychosis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics Tool for EphA5 Antibody (FAB541H)

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Bioinformatics

Gene Symbol EPHA5