EME1 Antibody

Images

 
Western Blot: EME1 Antibody [NBP1-32024] - Sample (30 ug of whole cell lysate) A: H1299 7.5% SDS PAGE; antibody diluted at 1:1000.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

EME1 Antibody Summary

Immunogen
Recombinant protein encompassing a sequence within the center region of human EME1. The exact sequence is proprietary.
Localization
Nucleus, nucleolus
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
EME1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:3000
Theoretical MW
63 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.0), 1.0% BSA and 20% Glycerol
Preservative
0.01% Thimerosal
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for EME1 Antibody

  • crossover junction endonuclease EME1
  • EC 3.1.22
  • EC 3.1.22.-
  • essential meiotic endonuclease 1 homolog 1 (S. pombe)
  • essential meiotic endonuclease 1 homolog 2
  • FLJ31364
  • hMMS4
  • homolog of yeast EME1 endonuclease
  • MMS4 homolog
  • MMS4
  • MMS4L
  • SLX2 structure-specific endonuclease subunit homolog A
  • SLX2A

Background

EME1 and MUS81 (MIM 606591) form an endonuclease complex that cleaves branched DNA structures, especially those arising during stalled DNA replication (Abraham et al., 2003 [PubMed 14609959]).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol EME1