EME1 Products

Description

EME1 and MUS81 (MIM 606591) form an endonuclease complex that cleaves branched DNA structures, especially those arising during stalled DNA replication (Abraham et al., 2003 [PubMed 14609959]).[supplied by OMIM]

Bioinformatics

Entrez	146956 Human
Uniprot	NP_689676 Human Q96AY2 Human AAH16470.1 Human
Product By Gene ID	146956
Alternate Names	EC 3.1.22 MMS4 EC 3.1.22.- MMS4 homolog SLX2 structure-specific endonuclease subunit homolog A hMMS4 homolog of yeast EME1 endonuclease SLX2A essential meiotic endonuclease 1 homolog 2 MMS4L crossover junction endonuclease EME1 FLJ31364 essential meiotic endonuclease 1 homolog 1 (S. pombe)

Diseases related to EME1

Discover more about diseases related to EME1.

Malignant Neoplasms
Genomic Instability
Neoplasms
Cell Transformation, Neoplastic
Malignant Tumor Of Colon
Haploinsufficiency
Cell Invasion
Fanconi Anemia
Glioblastoma Multiforme
Hereditary Diseases
Congenital Abnormality
Anemia
Glioma
Glioblastoma
Polyploidy
Brain Neoplasms
Pancytopenia
Immunologic Deficiency Syndromes
Bloom Syndrome
Tumor Escape

Pathways for EME1

View related products by pathway and learn more about each of the pathways below.

Dna Replication
Dna Repair
Meiosis
S Phase
Hypersensitivity
Gene Conversion
Cell Cycle
Localization
Mismatch Repair
Transport
Cell Cycle Checkpoint
Dna Recombination
Chromosome Segregation
V(d)j Recombination
Double-strand Break Repair
Strand Invasion
Translation
Dna Damage Checkpoint
Chromatin Modification
Response To Hydroxyurea

Research Areas for EME1

Find related products by research area and learn more about each of the different research areas below.

DNA Repair
Homologous Recombination

PTMs for EME1

Learn more about PTMs related to EME1.

Cleavage
Phosphorylation
Ubiquitination

Bioinformatics Tool for EME1

Discover related pathways, diseases and genes to EME1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.