eIF2B3 Antibody (24GB8150)

• Reactivity: Hu, Mu, Rt
• Applications: WB, Flow, Mycoplasma
• Clone: 24GB8150
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated

eIF2B3 Antibody (24GB8150) Summary

• Description: Reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.
• Immunogen: Recombinant protein of human eIF2B3 (Uniprot: Q9NR50)
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: EIF2B3
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry
  • Knockdown Validated
  • Western Blot

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4), 50% glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for eIF2B3 Antibody (24GB8150)

• eIF-2B GDP-GTP exchange factor subunit gamma
• EIF-2B
• EIF2Bgamma
• eukaryotic translation initiation factor 2B, subunit 3 (gamma, 58kD)
• eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa
• translation initiation factor eIF-2B subunit gamma

Background

The protein encoded by the eIF2B3 gene is one of the subunits of initiation factor eIF2B, which catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. It has also been found to function as a cofactor of hepatitis C virus internal ribosome entry site-mediated translation. Mutations in this gene have been associated with leukodystrophy with vanishing white matter. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: EIF2B3