EB3 Antibody [PE]

Product Discontinued

EB3 Antibody [PE] Summary

• Immunogen: Produced in rabbits immunized with purified, recombinant Human EB3 (Uniprot#: Q9UPY8-1; Met1-Tyr281)
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: MAPRE3
• Purity: Antigen and protein A Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Antigen and protein A Affinity-purified

Alternate Names for EB3 Antibody [PE]

• EB1 protein family member 3
• EB3EBF3-S
• End-binding protein 3
• microtubule-associated protein RP/EB family member 3
• microtubule-associated protein, RP/EB family, member 3
• RP3EBF3APC binding protein

Background

EB3 is a 282 amino acid homologue of EB1, a protein known to bind APC (adenomatous polyposis coli). It has been shown to bind to tubulin in vitro and microtubules in vivo. Northern blotting shows expressions to be mainly in brain, and to a lesser degree in muscle. EB3 interacts with APCL, a homologue of the tumor suppressor APC, and this interaction may be involved in the stabilization or extension of microtubules.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: MAPRE3