DYRK3 Antibody [DyLight 405]

Product Discontinued

DYRK3 Antibody [DyLight 405] Summary

• Immunogen: Synthetic peptide made to an internal portion of human DYRK3 (within residues 500-600). [Swiss-Prot# O43781]
• Localization: Nucleus.
• Predicted Species: Bovine (94%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: DYRK3
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot
• Application Notes: This DYRK3 antibody is useful for Immunocytochemistry/Immunofluorescence and Western blot, where a band is seen ~65 kDa. In ICC/IF distinct nuclear staining along with general cytoplasmic staining was observed in Hela cells.
  
  The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for DYRK3 Antibody [DyLight 405]

• dual specificity tyrosine-phosphorylation-regulated kinase 3
• dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
• dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 5
• DYRK3
• DYRK5
• EC 2.7.12
• EC 2.7.12.1
• hYAK3-2
• protein kinase Dyrk3
• REDK
• REDKRED
• Regulatory erythroid kinase
• YAK3-2

Background

DYRK3, or dual specificity tyrosine-phosphorylation-regulated kinase 3, is a negative regulator of EPO-dependent erythropoiesis and may place an upper limit on red cell production during stress erythropoiesis. DYRK3 inhibits cell death due to cytokine withdrawal in hematopoietic progenitor cells, and may also act by regulating CREB/CRE signaling.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: DYRK3