DYRK3 Antibody [FITC]

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Product Details

Summary
Reactivity Hu, Pm, Mu(-), Rt(-), BvSpecies Glossary
Applications ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
FITC

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Catalog# & Conjugate Size Price

DYRK3 Antibody [FITC] Summary

Immunogen
Synthetic peptide made to an internal portion of human DYRK3 (within residues 500-600). [Swiss-Prot# O43781]
Localization
Nucleus.
Predicted Species
Bovine (94%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
DYRK3
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/Immunofluorescence
Application Notes
This DYRK3 antibody is useful for Immunocytochemistry/Immunofluorescence and Western blot, where a band is seen ~65 kDa. In ICC/IF distinct nuclear staining along with general cytoplasmic staining was observed in Hela cells.

The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Theoretical MW
65 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Human and monkey. Does not react with mouse and rat. Immunogen sequence has 94% homology to bovine.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes

This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for DYRK3 Antibody [FITC]

  • dual specificity tyrosine-phosphorylation-regulated kinase 3
  • dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
  • dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 5
  • DYRK3
  • DYRK5
  • EC 2.7.12
  • EC 2.7.12.1
  • hYAK3-2
  • protein kinase Dyrk3
  • REDK
  • REDKRED
  • Regulatory erythroid kinase
  • YAK3-2

Background

DYRK3, or dual specificity tyrosine-phosphorylation-regulated kinase 3, is a negative regulator of EPO-dependent erythropoiesis and may place an upper limit on red cell production during stress erythropoiesis. DYRK3 inhibits cell death due to cytokine withdrawal in hematopoietic progenitor cells, and may also act by regulating CREB/CRE signaling.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol DYRK3
Entrez