DYRK3 Antibody


Western Blot: DYRK3 Antibody [NB110-94876] - Detection of DYRK3 in Jurkat nuclear extracts using NB110-94876.
Immunocytochemistry/ Immunofluorescence: DYRK3 Antibody [NB110-94876] - DYRK3 antibody was tested in Hela cells with DyLight 488 (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and Dylight 550 ...read more

Product Details

Reactivity Hu, Pm, Mu(-), Rt(-)Species Glossary
Applications WB, ICC/IF
1 mg/ml

Order Details

Available Conjugates
Catalog# & Conjugate Size Price

DYRK3 Antibody Summary

Synthetic peptide made to an internal portion of human DYRK3 (within residues 500-600). [Swiss-Prot# O43781]
Predicted Species
Bovine (94%)
Immunogen affinity purified
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Packaging, Storage & Formulations

Store at 4C. Do not freeze.
Tris-citrate/phosphate, pH 7-8
0.1% Sodium Azide
1 mg/ml
Immunogen affinity purified


Application Notes
This DYRK3 antibody is useful for Immunocytochemistry/Immunofluorescence and Western blot, where a band is seen ~65 kDa. In ICC/IF distinct nuclear staining along with general cytoplasmic staining was observed in Hela cells.

The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Theoretical MW
65 kDa

Reactivity Notes

Human and monkey. Does not react with mouse and rat. Immunogen sequence has 94% homology to bovine.

Alternate Names for DYRK3 Antibody

  • dual specificity tyrosine-phosphorylation-regulated kinase 3
  • dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
  • dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 5
  • DYRK5
  • EC 2.7.12
  • EC
  • hYAK3-2
  • protein kinase Dyrk3
  • REDK
  • Regulatory erythroid kinase
  • YAK3-2


DYRK3, or dual specificity tyrosine-phosphorylation-regulated kinase 3, is a negative regulator of EPO-dependent erythropoiesis and may place an upper limit on red cell production during stress erythropoiesis. DYRK3 inhibits cell death due to cytokine withdrawal in hematopoietic progenitor cells, and may also act by regulating CREB/CRE signaling.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

View specific protocols for DYRK3 Antibody (NB110-94876): Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for DYRK3 Antibody (NB110-94876). (Showing 1 - 1 of 1 FAQ).

  1. I am interested in Cat.No. NB110-94876 (anti-DYRK3) but would like to know if you have tested or if any feedback is available on the testing of this antibody with siRNA for DYRK3?
    • With regard to NB110-94876, we have not yet tested this product with an siRNA knockout or knockdown sample. Thus far, this antibody has been evaluated in western blot with Jurkat whole cell lysate and ICC with HeLa cells. We have also not had any publications submitted to us using this product.

Positive Control Lysate(s)

Secondary Antibodies


Isotype Controls

Other Available Formats

DyLight 405 Labeled NB110-94876V
FITC Labeled NB110-94876F

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Contact Information

Product PDFs


Gene Symbol DYRK3

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