DUSP12 Antibody

Images

 
Western Blot: DUSP12 Antibody [H00011266-D01P] - Analysis of DUSP12 expression in transfected 293T cell line by DUSP12 polyclonal antibody.Lane 1: DUSP12 transfected lysate(37.70 KDa).Lane 2: Non-transfected lysate.
Immunocytochemistry/ Immunofluorescence: DUSP12 Antibody [H00011266-D01P] - Analysis of antibody to DUSP12 on HeLa cell. Antibody concentration 20 ug/ml.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

DUSP12 Antibody Summary

Immunogen
DUSP12 (NP_009171.1, 1 a.a. ~ 340 a.a) full-length human protein.MLEAPGPSDGCELSNPSASRVSCAGQMLEVQPGLYFGGAAAVAEPDHLREAGITAVLTVDSEEPSFKAGPGVEDLWRLFVPALDKPETDLLSHLDRCVAFIGQARAEGRAVLVHCHAGVSRSVAIITAFLMKTDQLPFEKAYEKLQILKPEAKMNEGFEWQLKLYQAMGYEVDTSSAIYKQYRLQKVTEKYPELQNLPQELFAVDPTTVSQGLKDEVLYKCRKCRRSLFRSSSILDHREGSGPIAFAHKRMTPSS
Specificity
Reacts with dual specificity phosphatase 12.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
DUSP12
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • Western Blot
  • ELISA
  • Immunocytochemistry/Immunofluorescence
Application Notes
This antibody is reactive against transfected lysate in western blot, and as a detection antibody in ELISA.

Reactivity Notes

Human

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for DUSP12 Antibody

  • dual specificity phosphatase 12
  • dual specificity protein phosphatase 12
  • Dual specificity tyrosine phosphatase YVH1
  • DUSP1YVH1 protein-tyrosine phosphatase ortholog
  • EC 3.1.3.48
  • serine/threonine specific protein phosphatase
  • TDSP4
  • YVH1EC 3.1.3.16

Background

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is the human ortholog of the Saccharomyces cerevisiae YVH1 protein tyrosine phosphatase. It is localized predominantly in the nucleus, and is novel in that it contains, and is regulated by a zinc finger domain. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol DUSP12
Entrez
Uniprot