DUSP12 Products

Antibodies
DUSP12 Antibody
DUSP12 Antibody
NBP1-84961
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
DUSP12 Antibody
DUSP12 Antibody
H00011266-D01P
Species: Hu
Applications: WB, ELISA, ICC/IF
Host: Rabbit Polyclonal
DUSP12 Antibody
DUSP12 Antibody
H00011266-B01P
Species: Hu
Applications: WB, ELISA
Host: Mouse Polyclonal
Antibody Pairs
DUSP12 Antibody Pair
DUSP12 Antibody Pair
H00011266-PW1
Species: Hu
Applications: WB, IP
DUSP12 Antibody Pair
DUSP12 Antibody Pair
H00011266-AP21
Species: Hu
Applications: S-ELISA
Lysates
DUSP12 Overexpression Lysate ...
DUSP12 Overexpression Lysate (Native)
NBL1-10048
Applications: WB
DUSP12 Overexpression Lysate ...
DUSP12 Overexpression Lysate (Dena...
H00011266-T01
Applications: WB
Proteins
DUSP12 Recombinant Protein
DUSP12 Recombinant Protein
H00011266-P01
Species: Hu
Applications: WB, ELISA, PA
DUSP12 Partial Recombinant Pr ...
DUSP12 Partial Recombinant Protein
H00011266-Q01
Species: Hu
Applications: WB, ELISA, PA
DUSP12 Recombinant Protein An ...
DUSP12 Recombinant Protein Antigen
NBP1-84961PEP
Species: Hu
Applications: AC
RNAi
DUSP12 RNAi
DUSP12 RNAi
H00011266-R02
Species: Hu

Description

DUSP12 is encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is the human ortholog of the Saccharomyces cerevisiae YVH1 protein tyrosine phosphatase. It is localized predominantly in the nucleus, and is novel in that it contains, and is regulated by a zinc finger domain.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 11266
Alternate Names
  • TDSP4
  • dual specificity protein phosphatase 12
  • EC 3.1.3.48
  • Dual specificity tyrosine phosphatase YVH1
  • YVH1EC 3.1.3.16
  • DUSP1YVH1 protein-tyrosine phosphatase ortholog
  • serine/threonine specific protein phosphatase
  • dual specificity phosphatase 12

Research Areas for DUSP12

Find related products by research area and learn more about each of the different research areas below.

Protein Phosphatase

PTMs for DUSP12

Learn more about PTMs related to DUSP12.

Nitrosylation

Bioinformatics Tool for DUSP12

Discover related pathways, diseases and genes to DUSP12. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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