DSPP Antibody

Product Discontinued

DSPP Antibody Summary

• Immunogen: Synthetic peptide directed towards the C terminal of mouse 1110051B16RIK. Peptide sequence PTTTPGEQGFHSQPPLQLLTQNRGHNPRESGGLAVPRLEDCTQVPAVNQH.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: DSPP
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:1000
• Application Notes: This is a rabbit polyclonal antibody against 1110051B16RIK and was validated on Western blot.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS & 2% Sucrose.
• Preservative: 0.09% Sodium Azide
• Purity: Immunogen affinity purified

Notes

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Alternate Names for DSPP Antibody

• dentin phosphoprotein
• dentin sialophosphoprotein
• dentin sialoprotein
• DFNA39
• DMP3
• DTDP2

Background

The DSPP gene encodes two principal proteins of the dentin extracellular matrix of the tooth. The preproprotein is secretedby odontoblasts and cleaved into dentin sialoprotein and dentin phosphoprotein. Dentin phosphoprotein is thought to beinvolved in the bi

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for DSPP Antibody (NBP1-91612)(5)

Publications using NBP1-91612

• Zhang Y, Zhang H, Yuan G, Yang G IPO7 Promotes Odontoblastic Differentiation of Mouse Dental Papilla Cells by Selectively Importing Odontogenic Transcription Factors Research Square 2020-10-14 (WB, Mouse)
• Zhang Y, Zhang H, Xiao Z et al. IPO7 promotes odontoblastic differentiation and inhibits osteoblastic differentiation through regulation of RUNX2 expression and translocation Stem cells (Dayton, Ohio) 2022-08-03 [PMID: 35922041] (WB, Mouse)
• Liu Z, Lin Y, Fang X et al. Epigallocatechin-3-Gallate Promotes Osteo-/Odontogenic Differentiation of Stem Cells from the Apical Papilla through Activating the BMP-Smad Signaling Pathway Molecules 2021-03-12 [PMID: 33809391] (WB, Human)
• Zhang Y, Zhang H, Yuan G, Yang G Effects of transforming growth factor-beta 1 on odontoblastic differentiation in dental papilla cells is determined by IPO7 expression level Biochemical and biophysical research communications 2021-03-19 [PMID: 33548622] (WB, Mouse)
• Lin Y, Xiao Y, Lin C et al. SALL1 regulates commitment of odontoblast lineages by interacting with RUNX2 to remodel open chromatin regions J Immunol 2020-12-01 [PMID: 33159702] (WB, Mouse)

Bioinformatics

• Gene Symbol: DSPP
• Uniprot:
  • NP_899245(Mouse)