Drebrin 1 Antibody (M2F6)

Images

 
Western Blot: Drebrin 1 Antibody (M2F6) [NB100-1951] - Analysis of Drebrin expression in mouse brain (1) NIH/3T3 (2), Jurkat (3), HeLa (4), and PC12 (5)
Western Blot: Drebrin 1 Antibody (M2F6) [NB100-1951] - Analysis of mouse brain tissue extract probed with NB100-1951

Product Details

Summary
Reactivity Hu, Mu, Rt, Bv, Ch, Fe, RbSpecies Glossary
Applications WB, ICC/IF, IHC, IHC-P, IP
Clone
M2F6
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Order Details

Drebrin 1 Antibody (M2F6) Summary

Immunogen
Chicken Drebrin E protein.
Localization
Cytoplasmic
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
DBN1
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1ug/ml
  • Immunocytochemistry/Immunofluorescence
  • Immunohistochemistry 10 ug/ml
  • Immunohistochemistry-Paraffin 10 ug/ml
  • Immunoprecipitation
Application Notes
This antibody has been reported in the literature to work in IHC (PMID: 1314351).
Theoretical MW
110 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Control
Mouse Brain Whole Tissue Lysate (Adult Whole Normal)
Publications
Read Publications using NB100-1951.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 50% Glycerol
Preservative
No Preservative
Concentration
1.0 mg/ml
Purity
Protein A purified

Alternate Names for Drebrin 1 Antibody (M2F6)

  • D0S117E
  • DBN1
  • Developmentally-regulated brain protein
  • DKFZp434D064
  • Drba
  • Drebrin 1
  • Drebrin A
  • Drebrin E
  • Drebrin E2
  • drebrin
  • drebrin-1

Background

Drebrins are actin-binding proteins, that are developmentally regulated in the process of neuronal growth. Three isoforms, E1 and E2 (embryonic) and A (adult) are generated by alternative RNA splicing from a single debrin gene in the chicken brain. The expression pattern of each isoform is regulated spatially and temporally in the developing brain. It has been suggested that debrin is one of the intracellular regulators of the neuronal morphogenesis (4). Debrin has also been detected in other kinds of non-neuronal human and bovine tissue but its exact role is unknown.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Drebrin 1 Antibody (NB100-1951)(4)

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for Drebrin 1 Antibody (NB100-1951) (0)

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Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

Other Available Formats

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Bioinformatics

Gene Symbol DBN1
Entrez
Uniprot