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HAF007). A specific band was detected for Drebrin 1 at approximately 120 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1." class="big_lightbox" target="_blank">
NL007) and counterstained with DAPI (blue). Specific staining was localized to cell membrane and cytoplasm. View our protocol for Fluorescent ICC Staining of Cells on Coverslips." class="big_lightbox" target="_blank">
Drebrins are actin-binding proteins, that are developmentally regulated in the process of neuronal growth. Three isoforms, E1 and E2 (embryonic) and A (adult) are generated by alternative RNA splicing from a single debrin gene in the chicken brain. The expression pattern of each isoform is regulated spatially and temporally in the developing brain. It has been suggested that debrin is one of the intracellular regulators of the neuronal morphogenesis (4). Debrin has also been detected in other kinds of non-neuronal human and bovine tissue but its exact role is unknown.
![Western Blot Drebrin 1 Antibody (838102) [Unconjugated]](http://images.novusbio.com/images/antibody/Drebrin_1_MAB7739_Western_Blot_13062.jpg)
![Immunocytochemistry Drebrin 1 Antibody (838102) [Unconjugated]](http://images.novusbio.com/images/antibody/Drebrin_1_MAB7739_Immunocytochemistry_12983.jpg)
![Simple Western Drebrin 1 Antibody (838102) [Unconjugated]](http://images.novusbio.com/fullsize/antibody/Drebrin_1_MAB7739_Simple_Western_17664.jpg)
