Drebrin 1 Antibody (DBN-N-03) - BSA Free

Western Blot: Drebrin 1 Antibody (DBN-N-03) [NBP2-22344] - Drebrin Antibody (DBN-N-03) Western blotting analysis of drebrin expression in REH, Ramos, and Nalm-6 cell lysate using mouse monoclonal antibody.

Flow Cytometry: Drebrin 1 Antibody (DBN-N-03) [NBP2-22344] - Surface staining (mass cytometry) of brain tumor cells with anti-drebrin 152Sm. Gated on singlets.

• Reactivity: Hu
• Applications: WB, Flow, CyTOF-ready
• Clone: DBN-N-03
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1.0 mg/ml

Drebrin 1 Antibody (DBN-N-03) - BSA Free Summary

• Immunogen: Bacterially expressed N-terminal fragment of recombinant human Drebrin Antibody (DBN-N-03)
• Specificity: The mouse monoclonal Drebrin Antibody (DBN-N-03) recognizes drebrin, an approximately 100-125 kDa regulator of actin cytoskeleton.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: DBN1
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • CyTOF-ready
  • Flow (Intracellular) 1-4 ug/ml
  • Flow Cytometry 1-4 ug/ml
  • Western Blot
• Application Notes: This antibody is Cytof ready.
• Theoretical MW: 125 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: TBS (pH 8.0)
• Preservative: 0.09% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Protein A purified

Alternate Names for Drebrin 1 Antibody (DBN-N-03) - BSA Free

• D0S117E
• DBN1
• Developmentally-regulated brain protein
• DKFZp434D064
• Drba
• Drebrin 1
• Drebrin A
• Drebrin E
• Drebrin E2
• drebrin
• drebrin-1

Background

Drebrins are actin-binding proteins, that are developmentally regulated in the process of neuronal growth. Three isoforms, E1 and E2 (embryonic) and A (adult) are generated by alternative RNA splicing from a single debrin gene in the chicken brain. The expression pattern of each isoform is regulated spatially and temporally in the developing brain. It has been suggested that debrin is one of the intracellular regulators of the neuronal morphogenesis (4). Debrin has also been detected in other kinds of non-neuronal human and bovine tissue but its exact role is unknown.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: DBN1