DR6/TNFRSF21 Antibody Pair

Product Discontinued

DR6/TNFRSF21 Antibody Pair Summary

• Description: Quality control test: Standard curve using mammalian expressed recombinant protein as an analyte. This antibody pair set comes with matched antibody pair to detect and quantify protein level of human TNFRSF21.
  
  
• Capture antibody: mouse monoclonal anti-TNFRSF21 (100 ug)
• Detection antibody: biotinylated mouse monoclonal anti-TNFRSF21 IgG1 Kappa (50 ug)
• Standard Curve Range: 0.3 ng/ml to 100 ng/ml
• Assay Type: Sandwich ELISA
• Clonality: Monoclonal
• Gene: TNFRSF21
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Sandwich ELISA 0.3 ng/ml - 100 ng/ml

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: Immunogen affinity purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for DR6/TNFRSF21 Antibody Pair

• BM-018
• CD358 antigen
• CD358
• Death receptor 6
• DR6
• DR6TNFR-related death receptor 6
• MGC31965
• TNFRSF21
• tumor necrosis factor receptor superfamily member 21
• tumor necrosis factor receptor superfamily, member 21

Background

Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain containing receptors, TNFR1 and Fas. Several novel death receptors including DR3, DR4, and DR5 were recently identified. A new death domain containing receptor in the TNFR family was cloned recently and termed DR6 for death receptor 6. Like TNFR1, DR6 interacts with death domain containing adapter molecule TRADD. Overexpression of DR6 induces apoptosis and activates NF-kB and JNK. DR6 is widely expressed inhuman tissues and cell lines. The ligand for DR6 hasnot been identified.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are guaranteed for 6 months from date of receipt.

Bioinformatics

• Gene Symbol: TNFRSF21