DPP6 Antibody

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Immunohistochemistry-Paraffin: DPP6 Antibody [NB110-55517] - Analysis of anti-DPP6 antibody with human brain, neurons at 20 ug/ml.

Product Details

Summary
Reactivity Hu, Mu, Rt, Bv, Eq, Mk, Pm, Rb, Xp, Po, OpSpecies Glossary
Applications IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

DPP6 Antibody Summary

Immunogen
Synthetic 18 amino acid peptide from extracellular domain of human DPP6.
Specificity
Human DPP6. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Predicted Species
Porcine (94%), Opossum (94%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
DPP6
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin 1:10-1:500
Application Notes
ICC: Unsuccessful results on Mouse hippocampal cultured neurons is reported by anonymous customer.
Publications
Read Publication using
NB110-55517 in the following applications:

Reactivity Notes

Chimpanzee, Gorilla, Gibbon, Marmoset. Predicted cross-reactivity based on sequence identity: Elephant (100%), Panda (100%), Platypus (94%), Lizard (94%), Turkey (89%), Chicken (89%), Zebrafish (89%), Stickleback (83%), Pufferfish (83%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for DPP6 Antibody

  • dipeptidyl aminopeptidase IV-related protein
  • dipeptidyl aminopeptidase-like protein 6
  • Dipeptidyl aminopeptidase-related protein
  • Dipeptidyl peptidase 6
  • Dipeptidyl peptidase IV-like protein
  • dipeptidyl peptidase IV-related protein
  • Dipeptidyl peptidase VI
  • dipeptidylpeptidase 6
  • dipeptidyl-peptidase 6
  • dipeptidylpeptidase VI
  • DPP VI
  • DPP6
  • DPPX
  • DPPXFLJ55680
  • MGC46605
  • VF2

Background

DPP6 (DPPX, also known as potassium channel accelerating factor Dppx) is a Type-II serine proteinase of the clan SC. The clan SC proteinases have a catalytic triad of Ser-Asp-His, and like other Serine proteinases, the active site serine is in a Gly-Xaa-Ser-Xaa -Gly orientation. DPP6 has an Asp instead of Ser in the catalytic site. DPP6 is a member of a broader family of dipeptidyl peptidases including DPP4, FAP/Seprase, DPP2, DPP8, DPP9, DPP10, which have differing substrate specificity and tissue localizations. The surface-bound DPP6 is a homodimer, and cleavage of in the stalk region releases a shed form of DPP6. The shed is the form found in serum. DPP6 has been found in highest abundance in the brain, but also in the kidney, liver and lung.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Species: Hu, Mu, Rt, Bv, Eq, Mk, Pm, Rb, Xp, Po, Op
Applications: IHC-P

Publications for DPP6 Antibody (NB110-55517)(1)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: IHC-P.


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IHC-P
(1)
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Human
(1)
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Secondary Antibodies

 

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Blogs on DPP6.

The role of DNMT3A in development
Epigenetics is the study of heritable change in gene activity despite alteration of the hosts DNA sequence.  Change in gene activity done independently of the DNA sequence is achieved by way of histone and DNA methylation.  Gene silencing in DNA ...  Read full blog post.

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Bioinformatics

Gene Symbol DPP6
Entrez
Uniprot