Calsenilin Antibody (2B3-A1)

Images

 
Western Blot: Calsenilin Antibody (2B3-A1) [H00030818-M01] - Analysis of KCNIP3 expression in transfected 293T cell line by CSEN monoclonal antibody (M01), clone 2B3-A1.Lane 1: KCNIP3 transfected lysate (Predicted MW: ...read more
Immunocytochemistry/ Immunofluorescence: Calsenilin Antibody (2B3-A1) [H00030818-M01] - Analysis of monoclonal antibody to CSEN on HeLa cell . Antibody concentration 10 ug/ml.
Immunoprecipitation: Calsenilin Antibody (2B3-A1) [H00030818-M01] - Analysis of KCNIP3 transfected lysate using anti-KCNIP3 monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with KCNIP3 MaxPab rabbit ...read more
Sandwich ELISA: Calsenilin Antibody (2B3-A1) [H00030818-M01] - Detection limit for recombinant GST tagged CSEN is approximately 0.1ng/ml as a capture antibody.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, ICC/IF, IP, S-ELISA
Clone
2B3-A1
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

Calsenilin Antibody (2B3-A1) Summary

Immunogen
CSEN (AAH12850, 1 a.a. ~ 256 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MQPAKEVTKASDGSLLGDLGHTPLSKKEGIKWQRPRLSRQALMRCCLVKWILSSTAPQGSDSSDSELELSTVRHQPEGLDQLQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYAQFFPQGDATTYAHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGYITKEEMLAIMKSIYDMMGRHTYPILREDAPAEHVERFFEKMDRNQDGVVTIEEFLEACQKDENIMSSMQLFENVI
Specificity
CSEN - calsenilin, presenilin binding protein, EF-hand transcription factor
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
KCNIP3
Purity
IgG purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA
  • Immunocytochemistry/Immunofluorescence
  • Immunoprecipitation
  • Sandwich ELISA
  • Western Blot 1:500
Application Notes
Antibody reactive against recombinant protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control. It is also useful for immunofluorescence.

Reactivity Notes

Human. Other species not tested.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
In 1x PBS, pH 7.4
Preservative
No Preservative
Purity
IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Calsenilin Antibody (2B3-A1)

  • calsenilin
  • calsenilin, presenilin-binding protein, EF hand transcription factor
  • CSEN MGC18289
  • DREAM
  • DREAMA-type potassium channel modulatory protein 3
  • KCHIP3 DRE-antagonist modulator
  • KChIP3
  • Kv channel interacting protein 3, calsenilin
  • Kv channel-interacting protein 3
  • potassium channel interacting protein 3

Background

This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins, which belong to the recoverin branch of the EF-hand superfamily. Members of this family are small calcium binding proteins containing EF-hand-like domains. They are integral subunit components of native Kv4 channel complexes that may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. The encoded protein also functions as a calcium-regulated transcriptional repressor, and interacts with presenilins. Alternatively spliced transcript variants encoding different isoforms have been described.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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ICC/IF Video Protocol

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol KCNIP3
Entrez
OMIM
Uniprot