DOK1 Antibody

Western Blot: DOK1 Antibody [H00001796-B01P] - Analysis of DOK1 expression in human spleen.

Western Blot: DOK1 Antibody [H00001796-B01P] - Western Blot analysis of DOK1 expression in transfected 293T cell line by DOK1 MaxPab polyclonal antibody. Lane 1: DOK1 transfected lysate (52.91 KDa). Lane 2: Non-transfected lysate.

Product Discontinued

DOK1 Antibody Summary

• Description: Quality control test: Antibody reactive against mammalian transfected lysate.
• Immunogen: DOK1 (NP_001372, 1 a.a. - 481 a.a.) full-length human protein. MDGAVMEGPLFLQSQRFGTKRWRKTWAVLYPASPHGVARLEFFDHKGSSSGGGRGSSRRLDCKVIRLAECVSVAPVTVETPPEPGATAFRLDTAQRSHLLAADAPSSAAWVQTLCRNAFPKGSWTLAPTDNPPKLSALEMLENSLYSPTWEGSQFWVTVQRTEAAERCGLHGSYVLRVEAERLTLLTVGAQSQILEPLLSWPYTLLRRYGRDKVMFSFEAGRRCPSGPGTFTFQTAQGNDIFQAVETAIHRQKAQGKAGQGHDVLRADSHEGEVAEGKLPSPPGPQELLDSPPALYAEPLDSLRIAPCPSQDSLYSDPLDSTSAQAGEGVQRKKPLYWDLYEHAQQQLLKAKLTDPKEDPIYDEPEGLAPVPPQGLYDLPREPKDAWWCQARVKEEGYELPYNPATDDYAVPPPRSTKPLLAPKPQGPAFPEPGTATGSGIKSHNSALYSQVQKSGASGSWDCGLSRVGTDKTGVKSEGST
• Specificity: Reacts with docking protein 1, 62kDa (downstream of tyrosine kinase 1).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Mouse
• Gene: DOK1
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: This antibody is reactive against transfected lysate in WB and as a detection antibody in ELISA.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for DOK1 Antibody

• docking protein 1 (downstream of tyrosine kinase 1)
• docking protein 1
• docking protein 1, 62kD (downstream of tyrosine kinase 1)
• docking protein 1, 62kDa (downstream of tyrosine kinase 1)
• Downstream of tyrosine kinase 1
• MGC117395
• MGC138860
• p62(dok)
• P62DOK
• pp62

Background

Docking protein 1 is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. Docking protein 1 contains a putative pleckstrin homology domain at the amino terminus and ten PXXP SH3 recognition motifs. Docking protein 2 binds p120 (RasGAP) from CML cells. It has been postulated to play a role in mitogenic signaling. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: DOK1
• Entrez:
  • 1796(Human)
• Uniprot:
  • NP_001372(Human)