DOCK4 Antibody [Janelia Fluor® 585]

Product Discontinued

DOCK4 Antibody [Janelia Fluor® 585] Summary

• Immunogen: The immunogen recognized by this antibody maps to a region between residue 1916 and 1966 of human dedicator of cytokinesis 4 using the numbering given in entry NP_055520.3 (GeneID 9732).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: DOCK4
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for DOCK4 Antibody [Janelia Fluor® 585]

• dedicator of cytokinesis 4
• dedicator of cytokinesis protein 4
• KIAA0716FLJ34238
• MGC134911
• MGC134912

Background

DOCK4 is a member of the dedicator of cytokinesis (DOCK) family and encodes a protein with a DHR-1 (CZH-1) domain, a DHR-2 (CZH-2) domain and an SH3 domain. This membrane-associated, cytoplasmic protein functions as a guanine nucleotide exchange factor and is involved in regulation of adherens junctions between cells. Mutations in this gene have been associated with ovarian, prostate, glioma, and colorectal cancers. Alternatively spliced variants which encode different protein isoforms have been described, but only one has been fully characterized.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: DOCK4