DNAH11 Antibody

• Reactivity: Hu, Mu, Bv, Ca
• Applications: ELISA
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated
• Concentration: 0.5 mg/ml

DNAH11 Antibody Summary

• Description: Please note, this antibody is considered Innovators Grade. Innovators Grade antibodies are generally unvalidated and require additional characterization for most new species/applications. Novus has made these antibodies available through our Innovators Reward program. Complete an online review with image, detailing your positive or negative results. In return, you receive a discount voucher for 100% of the purchase price of the reviewed product. Please contact us at innovators@novusbio.com for more details.
• Immunogen: Peptide with sequence C-ERFSQGSHRD corresponding to internal region according to NP_003768.2.
• Epitope: C-ERFSQGSHRD
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: DNAH11
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Peptide ELISA Detection limit 1:8000
• Application Notes: WB: Not yet tested - Our standard WB protocol would not expect to reliably detect proteins as large as the calculated size of 521 kDa band according to NP_003768.2.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for DNAH11 Antibody

• Axonemal beta dynein heavy chain 11
• axonemal
• CILD7Dnahc11
• Ciliary dynein heavy chain 11
• DNAHBLFLJ30095
• DNAHC11FLJ37699
• DNHBL
• dynein, axonemal, heavy chain 11
• dynein, axonemal, heavy polypeptide 11
• dynein, ciliary, heavy chain 11

Background

The DNAH11 gene encodes a member of the dynein heavy chain family. It is a microtubule-dependent motor ATPase and has been reported to be involved in the movement of respiratory cilia. Mutations in this gene have been implicated in causing Kartagener Syndrome (

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for DNAH11 Antibody (NBP1-52175)(1)

Publication using NBP1-52175

• Escudier E, Duquesnoy P, Papon JF, Amselem S. Ciliary defects and genetics of primary ciliary dyskinesia. Paediatr Respir Rev 2009-06-01 [PMID: 19410201]

Bioinformatics

• Gene Symbol: DNAH11
• Entrez:
  • 8701(Human)
  • 13411(Mouse)
• Uniprot:
  • NP_003768.2(Human)