DLX5 Antibody (712216) [Alexa Fluor® 750]

• Applications: ICC/IF
• Clone: 712216
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 750

DLX5 Antibody (712216) [Alexa Fluor® 750] Summary

• Immunogen: E. coli-derived recombinant human DLX5
  Asn216-Tyr289
  Accession # P56178
• Specificity: Detects human DLX5 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human DLX4 is observed.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Background

DLX5 (distal-less homeobox 5) is a 33-35 kDa member of the distal-less homeobox family of transcription factors. It is expressed in embryonic mesenchyme where it promotes cartilage and bone formation, and in nervous tissue where it promotes interneuron development. Human DLX5 is 289 amino acids (aa) in length. It contains one DNA-binding homeobox domain (aa 137-196) and two phosphorylation sites at Ser34 and Ser217 that, when utilized, increases transcriptional activity. DLX5 likely forms homodimers, and is known to heterodimerize with MSX-2. Over aa 216-289, human DLX5 shares 99% aa identity with mouse DLX5.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.