Dkk-3 Antibody (138728) [FITC]

• Reactivity: Hu
• Applications: ELISA, ELISA(Cap), ELISA(Det)
• Clone: 138728
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: FITC

Dkk-3 Antibody (138728) [FITC] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human Dkk-3
  Ala22-Ile350
  Accession # Q9UBP4.1
• Specificity: Detects human Dkk-3 in ELISAs. In direct ELISAs, no cross-reactivity with recombinant human Dkk-1, recombinant mouse (rm) Dkk-2, or rmDkk-3 is observed.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Gene: DKK3
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • ELISA Capture (Matched Antibody Pair)
  • ELISA Detection (Matched Antibody Pair)
  • ELISA Standard (Matched Pair)
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Alternate Names for Dkk-3 Antibody (138728) [FITC]

• dickkopf (Xenopus laevis) homolog 3
• dickkopf 3
• dickkopf homolog 3 (Xenopus laevis)
• Dickkopf-3
• dickkopf-related protein 3
• Dkk3
• Dkk-3
• hDkk-3
• regulated in glioma
• REIC
• REICdkk-3
• RIG
• RIG-like 5-6
• RIG-like 7-1

Background

DKK3 is a secreted protein that is a member of the dickkopf family. It contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: DKK3