Dfna5 Antibody - BSA Free

Immunohistochemistry: Dfna5 Antibody - BSA Free [NBP3-48021] - Immunohistochemistry of paraffin-embedded human brain using (Dfna5 antibody) at dilution of 1:100

Western Blot: Dfna5 Antibody - BSA Free [NBP3-48021] - Mouse lung tissue were subjected to SDS PAGE followed by western blot with (Dfna5 antibody) at dilution of 1:1000

• Reactivity: Hu, Mu, Rt
• Applications: WB, ELISA, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

Dfna5 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit Dfna5 Antibody - BSA Free (NBP3-48021) is a polyclonal antibody validated for use in IHC, WB and ELISA. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: deafness, autosomal dominant 5. (Uniprot# O60443)
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: GSDME
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunohistochemistry 1:50 - 1:200
  • Western Blot 1:500 - 1:2000
• Theoretical MW: 54 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS, 50% Glycerol, pH (7.3)
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for Dfna5 Antibody - BSA Free

• deafness, autosomal dominant 5
• DFNA5, deafness associated tumor suppressor
• gasdermin-E
• ICERE1
• ICERE-1
• Inversely correlated with estrogen receptor expression 1
• non-syndromic hearing impairment protein 5
• nonsyndromic hearing impairment protein

Background

Hearing impairment is a heterogeneous condition with over 40 loci described. The protein encoded by this gene is expressed in fetal cochlea, however, its function is not known. Nonsyndromic hearing impairment is associated with a mutation in this gene. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GSDME