Desert Hedgehog/Dhh 293T Cell Transient Overexpression Lysate Summary
Description |
Quality control test: Transient overexpression cell lysate was tested with Anti-DHH antibody by Western Blots. Plasmid: pCMV-DHH full-length |
Specificity |
Desert Hedgehog/Dhh 293T Cell Transient Overexpression Lysate(Denatured) |
Gene |
DHH |
Applications/Dilutions
Packaging, Storage & Formulations
Storage |
Store at -80C. Avoid freeze-thaw cycles. |
Buffer |
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue) |
Lysate Details for Array
Type |
293T Cell Transient Overexpression |
Protein State |
Denatured |
Notes
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for Desert Hedgehog/Dhh 293T Cell Transient Overexpression Lysate
Background
Dhh encodes a member of the Hedgehog family. The hedgehog gene family encodes signaling molecules that play an important role in regulating morphogenesis. This protein is predicted to be made as a precursor that is autocatalytically cleaved; the N-terminal portion is soluble and contains the signalling activity while the C-terminal portion is involved in precursor processing. More importantly, the C-terminal product covalently attaches a cholesterol moiety to the N-terminal product, restricting the N-terminal product to the cell surface and preventing it from freely diffusing throughout the organism. Defects in this protein have been associated with partial gonadal dysgenesis (PGD) accompanied by minifascicular polyneuropathy. This protein may be involved in both male gonadal differentiation and perineurial development. [provided by RefSeq]
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Lysates are
guaranteed for 6 months from date of receipt.
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