DAB2 Antibody

Western Blot: DAB2 Antibody [H00001601-B01P] - Analysis of DAB2 expression in human liver.

Immunocytochemistry/Immunofluorescence: DAB2 Antibody [H00001601-B01P] - Analysis of purified antibody to DAB2 on HeLa cell. (antibody concentration 10 ug/ml)

Western Blot: DAB2 Antibody [H00001601-B01P] - Analysis of DAB2 expression in HeLa.

Western Blot: DAB2 Antibody [H00001601-B01P] - Analysis of DAB2 expression in transfected 293T cell line by DAB2 polyclonal antibody. Lane 1: DAB2 transfected lysate(84.7 KDa). Lane 2: Non-transfected lysate.

Product Discontinued

DAB2 Antibody Summary

• Description: Quality control test: Antibody reactive against mammalian transfected lysate.
• Immunogen: DAB2 (AAH03064.1, 1 a.a. - 770 a.a.) full-length human protein. MSNEVETSATNGQPDQQAAPKAPSKKEKKKGPEKTDEYLLARFKGDGVKYKAKLIGIDDVPDARGDKMSQDSMMKLKGMAAAGRSQGQHKQRIWVNISLSGIKIIDEKTGVIEHEHPVNKISFIARDVTDNRAFGYVCGGEGQHQFFAIKTGQQAEPLVVDLKDLFQVIYNVKKKEEEKKKIEEASKAVENGSEALMILDDQTNKLKSGVDQMDLFGDMSTPPDLNSPTESKDILLVDLNSEIDTNQNSLRENPFLTNGITSCSLPRPTPQASFLPENAFSANLNFFPTPNPDPFRDDPFTQPDQSTPSSFDSLKSPDQKKENSSSSSTPLSNGPLNGDVDYFGQQFDQISNRTGKQEAQAGPWPFSSSQTQPAVRTQNGVSEREQNGFSVKSSPNPFVGSPPKGLSIQNGVKQDLESSVQSSPHDSIAIIPPPQSTKPGRGRRTAKSSANDLLASDIFAPPVSEPSGQASPTGQPTALQPNPLDLFKTSAPAPVGPLVGLGGVTVTLPQAGPWNTASLVFNQSPSMAPGAMMGGQPSGFSQPVIFGTSPAVSGWNQPSPFAASTPPPVPVVWGPSASVAPNAWSTTSPLGNPFQSNIFPAPAVSTQPPSMHSSLLVTPPQPPPRAGPPKDISSDAFTALDPLGDKEIKDVKEMFKDFQLRQPPAVPARKGEQTSSGTLSAFASYFNSKVGIPQENADHDDFDANQLLNKINEPPKPAPRQVSLPVTKSTDNAFENPFFKDSFGSSQASVASSQPVSSEMYRDPFGNPFA
• Isotype: IgG
• Clonality: Polyclonal
• Host: Mouse
• Gene: DAB2
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot
• Application Notes: It has been used for WB and IF.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein G purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for DAB2 Antibody

• DAB2
• Differentially-expressed protein 2
• disabled (Drosophila) homolog 2 (mitogen-responsive phosphoprotein)
• disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
• Disabled-2
• DOC2
• DOC-2DOC2disabled homolog 2
• FLJ26626
• mitogen-responsive phosphoprotein

Background

Disabled-2 (Dab2) is a component of the CSF-1 signal transduction pathway. Dab2 is involved in the regulation of cytoskeleton based functions by regulating cell positioning, inducing marcrophage adhesion, or regulation of protein trafficking of endocytosis involved proteins (1,2). Dab2 has been implicated in regulating the homeostasis of epithelial differentiation, where Dab2 is involved in endodermal cell formation, differentiation, and organization. Dab2 mRNA expression is common in normal ovarian epithelia cells but low or lack of expression is seen in ovarian carcinoma cell lines (3).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: DAB2
• Uniprot:
  • AAH03064.1(Human)