Cytohesin 4 Antibody

Product Discontinued

Cytohesin 4 Antibody Summary

• Immunogen: Peptide with sequence DCFESAEESRMAQ corresponding to internal region according to NP_037517.1.
• Epitope: internal region
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: CYTH4
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Peptide ELISA Detection limit 1:32000
• Application Notes: WB: Preliminary experiments in human lysates of peripheral blood mononucleocytes gave no specific signal but low background.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Notes

Please note, this antibody is considered Innovators Grade. Innovators Grade antibodies are generally unvalidated and require additional characterization for most new species/applications. Novus has made these antibodies available through our Innovators Reward program. Complete an online review with image, detailing your positive or negative results. In return, you receive a discount voucher for 100% of the purchase price of the reviewed product. Please contact us at innovators@novusbio.com for more details.

Alternate Names for Cytohesin 4 Antibody

• CYT4PH, SEC7 and coiled-coil domain-containing protein 4
• cytohesin 4
• cytohesin-4
• pleckstrin homology, Sec7 and coiled/coil domains 4
• pleckstrin homology, Sec7 and coiled-coil domains 4
• PSCD4DJ63G5.1

Background

The protein encoded by this gene is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. The encoded protein exhibits GEP activity in vitro with both ARF1 and ARF5 but is inactive with ARF6. The structures of this gene and CYTH1 are very similar.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Cytohesin 4 Antibody (NBP1-28493)(1)

Publication using NBP1-28493

• Wenzler M, Brunner E, Kroger N et al. Letter to the Editor: 1H, 13C and 15N sequence-specific resonance assignment of the PSCD4 domain of diatom cell wall protein pleuralin-1. J Biomol NMR 2001-06-01 [PMID: 11495255]

Bioinformatics

• Gene Symbol: CYTH4
• Entrez:
  • 27128(Human)
  • 72318(Mouse)
  • 500906(Rat)
• Uniprot:
  • NP_037517.1(Human)