Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF, IHC
Host: Mouse Monoclonal
Species: Hu, Rt
Applications: WB, ELISA, ICC/IF
Host: Mouse Monoclonal
Species: Hu, Mu, Rt, Po, Ca
Applications: WB, ELISA
Host: Goat Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: PAGE
Species: Hu
Applications: AC
Description
Pleckstrin homology, Sec7 and coiled/coil domains 2 (PSCD2) is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. PSCD2 exhibits GEP activity in vitro with ARF1, ARF3, and ARF6. PSCD2 protein is 83% homologous to PSCD1. Two transcript variants encoding different isoforms have been found for this gene.
Bioinformatics
| Entrez |
Rat
Mouse
Human
|
| Uniprot |
Human
Human
Human
|
| Product By Gene ID |
9266 |
| Alternate Names |
- ARF exchange factor
- ARF nucleotide-binding site opener
- ARNOPH, SEC7 and coiled-coil domain-containing protein 2
- CTS18.1
- cytohesin 2
- pleckstrin homology, Sec7 and coiled-coil domains 2 (cytohesin-2)
- Protein ARNO
- PSCD2LCTS18
- PSCD2pleckstrin homology, Sec7 and coiled-coil domains 2
- Sec7 and coiled/coil domains 2 (cytohesin-2)
|
