CYP26A1 Antibody - BSA Free

Western Blot: CYP26A1 Antibody [NBP2-16061] - Various whole cell extracts (30 ug) were separated by 10% SDS-PAGE, and the membrane was blotted with CYP26A1 antibody diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (NBP2-19301) was used to detect the primary antibody.

Western Blot: CYP26A1 Antibody [NBP2-16061] - Mouse tissue extract (50 ug) was separated by 10% SDS-PAGE, and the membrane was blotted with CYP26A1 antibody diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (NBP2-19301) was used to detect the primary antibody.

Immunohistochemistry-Paraffin: CYP26A1 Antibody [NBP2-16061] - CYP26A1 antibody detects CYP26A1 protein at cytoplasm by immunohistochemical analysis.Sample: Paraffin-embedded mouse brain.CYP26A1 stained by CYP26A1 antibody (NBP2-16061) diluted at 1:500.Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

Western Blot: CYP26A1 Antibody [NBP2-16061] - Mouse tissue extract (50 ug) was separated by 10% SDS-PAGE, and the membrane was blotted with CYP26A1 antibody (NBP2-16061) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.

• Reactivity: Hu, Mu, Rt, Po, Bv, RM
• Applications: WB, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

CYP26A1 Antibody - BSA Free Summary

• Immunogen: Recombinant protein encompassing a sequence within the center region of human CYP26A1. The exact sequence is proprietary.
• Localization: Endoplasmic reticulum membrane; Microsome membrane
• Predicted Species: Rat (92%), Porcine (97%), Bovine (96%), Rhesus Macaque (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CYP26A1
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:100-1:1000
  • Immunohistochemistry-Paraffin 1:100-1:1000
  • Western Blot 1:500-1:3000
• Theoretical MW: 56 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Chicken (83%).

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS, 20% Glycerol
• Preservative: 0.025% Proclin 300
• Purity: Antigen Affinity-purified

Alternate Names for CYP26A1 Antibody - BSA Free

• CP26
• CYP26Retinoic acid 4-hydroxylase
• cytochrome P450 26A1
• Cytochrome P450 retinoic acid-inactivating 1
• cytochrome P450, family 26, subfamily A, polypeptide 1
• cytochrome P450, subfamily XXVIA, polypeptide 1
• Cytochrome P450RAI
• EC 1.14
• hP450RAI
• P450, retinoic acid-inactivating, 1
• P450RAI
• P450RAI1Retinoic acid-metabolizing cytochrome

Background

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein acts on retinoids, including all-trans-retinoic acid (RA), with both 4-hydroxylation and 18-hydroxylation activities. This enzyme regulates the cellular level of retinoic acid which is involved in regulation of gene expression in both embryonic and adult tissues. Two alternatively spliced transcript variants of this gene, which encode the distinct isoforms, have been reported. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

Publications for CYP26A1 Antibody (NBP2-16061)(1)

Publication using NBP2-16061

• Goyon V, Besse-Patin A, Zunino R et al. MAPL loss dysregulates bile and liver metabolism in mice EMBO reports 2023-11-14 [PMID: 37962001] (WB, Mouse)

Bioinformatics

• Gene Symbol: CYP26A1
• Uniprot:
  • O43174(Human)