Recombinant Human CXCL1/GRO alpha/KC/CINC-1 Protein

Product Discontinued

Recombinant Human CXCL1/GRO alpha/KC/CINC-1 Protein Summary

• Description: A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 35-107 of Human GRO alpha
  
  

  Source: E.coli

  Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MASVATELRC QCLQTLQGIH PKNIQSVNVK SPGPHCAQTE VIATLKNGRK ACLNPASPIV KKIIEKMLNS DKSN

• Source: E. coli
• Protein/Peptide Type: Recombinant Protein
• Gene: CXCL1
• Purity: >90%, by SDS-PAGE
• Endotoxin Note: < 1.0 EU per 1 microgram of protein (determined by LAL method)

Applications/Dilutions

• Dilutions:
  • SDS-Page
• Theoretical MW: 10.1 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 20 mM Tris-HCl buffer (pH 8.0), 10% glycerol
• Preservative: No Preservative
• Concentration: 1 mg/ml
• Purity: >90%, by SDS-PAGE

Alternate Names for Recombinant Human CXCL1/GRO alpha/KC/CINC-1 Protein

• CINC1
• CINC-1
• CXCL1
• FSP
• GRO alpha
• GRO1
• GROa
• KC
• MGSA
• MGSA-a
• MGSA-alpha
• NAP-3
• SCYB1

Background

CXCL1/GROa is a growth factor for melanoma cells and a chemotaxin for neutrophils. Similar to other alpha chemokines, this protein is potent neutrophil attractant and activator and is also active toward basophils. In addition, CXCL1 protein may be a therapeutic target as well as a diagnostic marker in ovarian cancer. Recombinant CXCL1 protein was expressed in E.coli and purified by using conventional chromatography techniques

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: CXCL1