CTDSP1 Antibody [DyLight 594]

Product Discontinued

CTDSP1 Antibody [DyLight 594] Summary

• Immunogen: CTD(carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1. (Uniprot# Q9GZU7)
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CTDSP1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for CTDSP1 Antibody [DyLight 594]

• carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1
• CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) smallphosphatase 1
• NIF3
• NLI-IF
• NLIIFEC 3.1.3.16
• NLI-interacting factor 3
• SCP1Nuclear LIM interactor-interacting factor 3
• Small CTD phosphatase 1
• Small C-terminal domain phosphatase 1

Background

Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residues repeats in theC-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase IItranscription, possibly by controlling the transition from initiation/capping to processive transcript elongation.Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronalcells

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CTDSP1