CTDSP1 Products

Description

Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residues repeats in theC-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase IItranscription, possibly by controlling the transition from initiation/capping to processive transcript elongation.Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronalcells

Bioinformatics

Entrez	227292 Mouse 58190 Human
Uniprot	NM_021198 Human NM_182642 Human NP_067021 Human NP_067021.1 Human NP_872580 Human NP_872580.1 Human Q9GZU7 Human
Product By Gene ID	58190
Alternate Names	carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) smallphosphatase 1 NIF3 NLI-IF NLIIFEC 3.1.3.16 NLI-interacting factor 3 SCP1Nuclear LIM interactor-interacting factor 3 Small CTD phosphatase 1 Small C-terminal domain phosphatase 1