CSAD Antibody (P8G6)

Product Discontinued

CSAD Antibody (P8G6) Summary

• Immunogen: IL-1beta activated HUVEC (human).
• Specificity: Human P Selectin.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: CSAD
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Immunocytochemistry/ Immunofluorescence 1:10-1:500
  • Immunohistochemistry 1:10-1:500
  • Immunoprecipitation 1:10-1:500
• Application Notes: Immunohistochemistry: for use on acetone or paraformaldehyde fixed tissue. Immunocytochemistry/Immunofluorescence ,Immunoprecipitation and ELISA Inhibits P Selectin dependent interactions Inhibits platelet binding to monocytes

Reactivity Notes

Human

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: 20mM Phosphate (pH 7.6) and 0.25M NaCl
• Preservative: 0.1% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Protein A or G purified

Notes

Relevant Entrez Gene Numbers: NM_003006.3

Alternate Names for CSAD Antibody (P8G6)

• CSDMGC119355
• cysteine sulfinic acid decarboxylase
• Cysteine-sulfinate decarboxylase
• EC 4.1.1
• EC 4.1.1.29
• FLJ44987
• FLJ45500
• MGC119354
• MGC119357
• PCAP
• P-selectin cytoplasmic tail-associated protein
• Sulfinoalanine decarboxylase

Background

CSAD, also known as Cysteine sulfinic acid decarboxylase-related protein, consists of a 582 amino acid isoform that is 64 kDa, and is involved in the process through which cysteinesulfinate undergoes decarboxylation to produce hypotaurine. Current research is being conducted on CSAD to determine its relation to several diseases and disorders, including pulmonary edema, stiff-person syndrome, hepatocellular carcinoma, prostate cancer, seizures, and autoimmune diseases. CSAD interacts with SMN1, SMN2, ANXA1, ANXA7, and CDKN1A in several metabolic pathways and taurine biosynthesis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CSAD
• Uniprot:
  • Q14242()