CRHR1/CRF1 Antibody (343919) [Alexa Fluor™ Plus 555]

• Reactivity: Hu
• Clone: 343919
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor Plus 555

CRHR1/CRF1 Antibody (343919) [Alexa Fluor™ Plus 555] Summary

• Specificity: Detects human CRHR‑1 transfectants but not irrelevant transfectants.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for CRHR1/CRF1 Antibody (343919) [Alexa Fluor™ Plus 555]

• CHR-R1
• corticotropin releasing hormone receptor 1
• corticotropin-releasing factor receptor 1
• corticotropin-releasing factor type 1 receptor
• Corticotropin-releasing hormone receptor 1
• CRF1
• CRFR
• CRF-R
• CRFR1
• CRF-R1
• CRF-R-1
• CRFR-1
• CRHR1
• CRH-R-1
• CRHR1f
• CRH-R1h
• CRHR1L
• CRHRCRH-R1
• seven transmembrane helix receptor

Background

Corticotrophin-Releasing Hormone Receptor 1 (CRHR-1), also known as CRFR-1, is a 7TM protein that belongs to the G protein-coupled receptor family 2. CRHR-1 is expressed in the brain and adrenal gland where it mediates corticotropin-induced effects on anxiety, depression, and stress-associated pathologies. The immunogen for this antibody corresponds to one of the four alternately spliced forms and has a 29 amino acid deletion in the first cytoplasmic domain. Human CRHR-1 shares 97% amino acid sequence identity with mouse and rat CRHR-1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.