CRHBP Antibody (395108) [Janelia Fluor® 525]

• Reactivity: Hu
• Applications: WB
• Clone: 395108
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Janelia Fluor 525

CRHBP Antibody (395108) [Janelia Fluor® 525] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human CRHBP
  Tyr25-Leu322
  Accession # P24387
• Specificity: Detects human CRHBP in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant mouse CRHBP is observed.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: CRHBP
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for CRHBP Antibody (395108) [Janelia Fluor® 525]

• corticotropin releasing hormone binding protein
• corticotropin-releasing factor-binding protein
• Corticotropin-releasing hormone-binding protein
• CRFBP
• CRFBPcorticotropin releasing hormone-binding protein
• CRF-BPCRF-binding protein
• CRHBP
• CRH-BP

Background

Corticotropin-releasing hormone is a potent stimulator of synthesis and secretion of preopiomelanocortin-derived peptides. Although CRH concentrations in the human peripheral circulation are normally low, they increase throughout pregnancy and fall rapidly after parturition. Maternal plasma CRH probably originates from the placenta. Human plasma contains a CRH-binding protein which inactivates CRH and which may prevent inappropriate pituitary-adrenal stimulation in pregnancy. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CRHBP