Complement Factor MASP3/MASP1 Antibody [Janelia Fluor® 525]

• Reactivity: Hu
• Applications: WB, IP
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Janelia Fluor 525

Complement Factor MASP3/MASP1 Antibody [Janelia Fluor® 525] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human Complement Factor MASP3
  Ile450-Val721
  Accession # NP_624302
• Specificity: Detects human Complement Factor MASP3 Catalytic Domain in direct ELISAs and Western blots.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: MASP1
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Antigen Affinity-purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Complement Factor MASP3/MASP1 Antibody [Janelia Fluor® 525]

• Complement Factor MASP3
• Complement factor MASP-3
• Complement-activating component of Ra-reactive factor
• CRARF1
• CRARFMAP1
• DKFZp686I01199
• EC 3.4.21
• EC 3.4.21.-
• EC 3.4.21.104
• EC 3.4.21.42
• FLJ26383
• mannan-binding lectin serine peptidase 1 (C4/C2 activating component ofRa-reactive factor)
• mannan-binding lectin serine protease 1 (C4/C2 activating component ofRa-reactive factor)
• mannan-binding lectin serine protease 1
• Mannose-binding lectin-associated serine protease 1
• Mannose-binding protein-associated serine protease
• MAp44
• MASP
• MASP1
• MASP-1
• MASP3
• MGC126283
• MGC126284
• PRSS5
• Ra-reactive factor serine protease p100
• RaRF
• Serine protease 5

Background

The Ra-reactive factor (RARF) is a complement-dependent bactericidal factor that binds to the Ra and R2 polysaccharides expressed by certain enterobacteria. Alternate splicing of this gene results in multiple transcript variants encoding two RARF components that are involved in the mannan-binding lectin (MBL) pathway of complement activation. Two of the isoforms are cleaved into two chains which form a heterodimer linked by a disulfide bond. The encoded proteins are members of the trypsin family of peptidases. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: MASP1